Daptomycin CAS 103060-53-3

Product Description:

Product Name: Daptomycin CAS NO: 103060-53-3

 

Synonyms:

Daptomycin,N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L- -aspartyl-L-threonylglycyl-L-ornithinyl-L- -aspartyl-D-alanyl-L- -aspartylglycyl-D-seryl-(3R)-3-methyl-L- -glutamyl- ,2-diamino- -oxo-benzenebutanoicacid(13-4)lactone;

Cidecin;

 

Chemical Physical Properties:

Appearance: White powder

Assay : Greater than or equal to 99.0 percent

Density: 1.45 g/cm3

Boiling Point: 2078.2 degree at 760 mmHg

Flash Point: 1210.7 degree

Refractive Index: 1.638

Vapor Pressure: 0mmHg at 25 degree

Storage temp.: Sealed in dry,Store in freezer, under -20 degree

Solubility: methanol: soluble5mg/mL

 

Safety Information:

WGK Germany: 3

RTECS: HB5626000

HS Code: 29419090

Toxicity: LD50 i.v. in mice: 600 mg/kg (Debono)

 

Daptomycin is a lipopeptide antibiotic used in the treatment of systemic and life-threatening infections caused by Gram-positive organisms. It is a naturally occurring compound found in the soil saprotroph Streptomyces roseosporus. Its distinct mechanism of action makes it useful in treating infections caused by multiple drug-resistant bacteria. It is marketed in the United States under the trade name Cubicin by Cubist Pharmaceuticals.

 

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